---
title: The cryoDuck Blog - Commentary on everything cryo-EM in drug discovery. | Mazdak Radjainia (7)
description: Mazdak Radjainia, the managing director of cryoDuck, has a rich background in cryo-EM spanning academia and industry. From his early days at Goethe University to managerial roles at Monash University and Thermo Fisher Scientific, he's always seen cryo-EM as a game of getting your ducks in a row. A firm believer in the power of collaboration and adaptability, he's dedicated to making cryo-EM's successes accessible to industrial users. With cryoDuck, he aims to fully industrialize Cryo-EM, paving the way for better, safer medicines. Follow his journey on the cryoDuck blog as he navigates the ever-evolving world of Cryo-EM in drug discovery. (7)
image: https://cryoduck.com/hubfs/4.png
---

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# The cryoDuck Blog

Commentary on everything related to cryo-EM in drug discovery.

[![repeat structures](https://cryoduck.com/hubfs/KEK%20webinar.png)](https://cryoduck.com/blog/schemes)

[advances in cryo-EM](https://cryoduck.com/blog/tag/advances-in-cryo-em), [cryo-EM industrialization](https://cryoduck.com/blog/tag/cryo-em-industrialization), [Clovertex](https://cryoduck.com/blog/tag/clovertex)

## [Automated RELION for repeat structures (Webinar July 26th)](https://cryoduck.com/blog/schemes)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jul 20, 2023 8:45:04 PM

What if we told you that an automated RELION workflow could potentially outperform human users in si...

[Read more](https://cryoduck.com/blog/schemes)

[![](https://cryoduck.com/hubfs/Hottest%20tweets-2-1.png)](https://cryoduck.com/blog/tweets-0723)

[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## [MiTeGen Hottest Tweets in SBDD (07/23)](https://cryoduck.com/blog/tweets-0723)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jul 15, 2023 10:11:01 PM

Here are your MiTeGen Hottest Tweets in SBDD, showcasing incredibly beautiful structures of targets,...

[Read more](https://cryoduck.com/blog/tweets-0723)

[![Clovertex PaaS](https://cryoduck.com/hubfs/PaaS.png)](https://cryoduck.com/blog/paas)

[cryoDuck ecosystem](https://cryoduck.com/blog/tag/cryoduck-ecosystem), [advances in cryo-EM](https://cryoduck.com/blog/tag/advances-in-cryo-em), [Clovertex](https://cryoduck.com/blog/tag/clovertex), [cloud](https://cryoduck.com/blog/tag/cloud), [iot cryo-em](https://cryoduck.com/blog/tag/iot-cryo-em)

## [Understanding Platform as a Service (PaaS) with Clovertex](https://cryoduck.com/blog/paas)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jul 4, 2023 2:37:05 PM

Following the previous discussions on IoT in Cryo-EM and the resurgence of the manual plunge cooler,...

[Read more](https://cryoduck.com/blog/paas)

[![chagas](https://cryoduck.com/hubfs/Chagas.png)](https://cryoduck.com/blog/chagas)

[cryo-EM in drug discovery](https://cryoduck.com/blog/tag/cryo-em-in-drug-discovery)

## [Novartis utilizes cryo-EM to understand new drug pathway for treating Chagas disease and sleeping sickness](https://cryoduck.com/blog/chagas)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jul 2, 2023 10:04:13 PM

Over a billion people across tropical and subtropical regions worldwide grapple with the severe heal...

[Read more](https://cryoduck.com/blog/chagas)

[![ETAR](https://cryoduck.com/hubfs/Target%20of%20the%20month-06.png)](https://cryoduck.com/blog/etar)

[Clovertex](https://cryoduck.com/blog/tag/clovertex), [gpcr](https://cryoduck.com/blog/tag/gpcr), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month)

## [Clovertex Target of the Month (06/23): Endothelin A Receptor](https://cryoduck.com/blog/etar)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jun 30, 2023 7:17:26 PM

For June 2023, we draw your attention to the Endothelin A Receptor (ETAR) as the 'Clovertex Drug Tar...

[Read more](https://cryoduck.com/blog/etar)

[![Renaissance plunge](https://cryoduck.com/hubfs/Renaissance.png)](https://cryoduck.com/blog/renaissance)

[cryoDuck ecosystem](https://cryoduck.com/blog/tag/cryoduck-ecosystem), [advances in cryo-EM](https://cryoduck.com/blog/tag/advances-in-cryo-em), [MiTeGen](https://cryoduck.com/blog/tag/mitegen), [iot cryo-em](https://cryoduck.com/blog/tag/iot-cryo-em)

## [Renaissance of the Manual Plunge Cooler](https://cryoduck.com/blog/renaissance)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jun 28, 2023 5:26:27 PM

In our previous exploration of IoT in cryo-EM, we illuminated how technology could democratize the f...

[Read more](https://cryoduck.com/blog/renaissance)

[![Ammunition](https://cryoduck.com/hubfs/Ammunition.png)](https://cryoduck.com/blog/ucp1)

[cryo-EM in drug discovery](https://cryoduck.com/blog/tag/cryo-em-in-drug-discovery), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets), [membrane protein](https://cryoduck.com/blog/tag/membrane-protein), [small targets](https://cryoduck.com/blog/tag/small-targets)

## [32 kDa UCP1: Sybody-LEGOBody strategy puts the journey from munitions workers to weight loss drug target in cryo-EM crosshairs](https://cryoduck.com/blog/ucp1)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jun 26, 2023 10:23:13 AM

From the trenches of World War I to the ongoing battle against obesity, the story of UCP1 is as capt...

[Read more](https://cryoduck.com/blog/ucp1)

[![smart fridge](https://cryoduck.com/hubfs/fridge.png)](https://cryoduck.com/blog/iot-cryoem)

[advances in cryo-EM](https://cryoduck.com/blog/tag/advances-in-cryo-em), [Clovertex](https://cryoduck.com/blog/tag/clovertex), [cloud](https://cryoduck.com/blog/tag/cloud), [iot cryo-em](https://cryoduck.com/blog/tag/iot-cryo-em)

## [Big in Japan: IoT cryo-EM as a leap towards ultimate automation](https://cryoduck.com/blog/iot-cryoem)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jun 22, 2023 10:17:45 PM

Whenever I hear about Internet of Things (IoT), I think of smart fridges that have been touted as th...

[Read more](https://cryoduck.com/blog/iot-cryoem)

[![Hottest tweets](https://cryoduck.com/hubfs/Hottest%20tweets-2.png)](https://cryoduck.com/blog/tweets-0623)

[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## [MiTeGen Hottest Tweets in SBDD (06/23)](https://cryoduck.com/blog/tweets-0623)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jun 19, 2023 6:56:11 PM

Introducing the Hottest Tweets in SBDD sponsored by MiTeGen, your curated source of recent tweets fo...

[Read more](https://cryoduck.com/blog/tweets-0623)

[![](https://cryoduck.com/hubfs/Trikafta.png)](https://cryoduck.com/blog/trikafta)

[cryo-EM in drug discovery](https://cryoduck.com/blog/tag/cryo-em-in-drug-discovery), [gene therapy](https://cryoduck.com/blog/tag/gene-therapy)

## [Trikafta: Visualizing three chemical tales in one](https://cryoduck.com/blog/trikafta)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jun 9, 2023 10:54:39 PM

Historically, cystic fibrosis (CF) has been among the most gruesome genetic diseases, often seen as ...

[Read more](https://cryoduck.com/blog/trikafta)

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