--- title: "Clovertex Target of the Month (01/25): D2R" description: Here's the January 2025 Clovertex target of the month. image: https://cryoduck.com/hubfs/D2R.png --- [Skip to content](https://cryoduck.com/blog/d2r#main-content) [![cryoDuck Logo](https://cryoduck.com/hs-fs/hubfs/Home/horizontal%20light%20bg.png?width=300&height=66&name=horizontal%20light%20bg.png)](https://cryoduck.com) - [Home](https://cryoduck.com/) - [About](https://cryoduck.com/about) - [Blog](https://cryoduck.com/blog) - [Newsletter](https://cryoduck.com/newsletter) Open main navigation Close main navigation - [Home](https://cryoduck.com/) - [About](https://cryoduck.com/about) - [Blog](https://cryoduck.com/blog) - [Newsletter](https://cryoduck.com/newsletter) - [Contact us](https://cryoduck.com/contact) [Contact us](https://cryoduck.com/contact) Feb 4, 2025 3:16:52 PM # Clovertex Target of the Month (01/25): D2R ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Share: [linkedin-in icon](http://www.linkedin.com/shareArticle?mini=true&url=https://cryoduck.com/blog/d2r) [Twitter icon](https://twitter.com/intent/tweet?url=https://cryoduck.com/blog/d2r) [envelope icon](mailto:?body=https://cryoduck.com/blog/d2r) Clovertex’s January Target of the Month is Dopamine D2 Receptor (D2R), highlighted by Johnson & Johnson’s $14.6 billion acquisition of Intra-Cellular Therapies, announced at the J.P. Morgan Healthcare Conference. D2R is a key receptor in the dopamine signaling pathway, playing a central role in schizophrenia, bipolar disorder, and other psychiatric conditions. The deal centers on lumateperone (Caplyta®), a next-generation antipsychotic that modulates D2R activity while also affecting serotonin pathways, offering a differentiated approach to treating severe mental illnesses. With this acquisition, J&J strengthens its position in neuroscience, reflecting the growing commercial interest in innovative psychiatric treatments. More importantly, it underscores the urgent need for better therapies in a space where millions still struggle with debilitating conditions including depression. ![D2R](https://cryoduck.com/hs-fs/hubfs/D2R.png?width=1200&height=627&name=D2R.png) The [Protein Imager](https://academic.oup.com/bioinformatics/article/36/9/2909/5701652?guestAccessKey=69bb093e-3b30-4468-ada7-3ea6ff198636&login=false) rendering displays the cryo-EM structure of native dystrophin-glycoprotein complex (PDB entry [8IRS](https://www.rcsb.org/structure/8IRS)).   ## About Clovertex Clovertex is an industry leader specializing in meeting the scientific IT needs of pharmaceutical companies, with a robust focus on cloud-based or on-premises cryo-EM processing. As an Advanced Tier Services Partner with Amazon Web Services (AWS), Clovertex leverages its comprehensive expertise to architect, build, automate, and manage software applications designed to meet specific research needs. Our all-encompassing solutions are meticulously tailored to streamline the complex processes associated with pharmaceutical research, underscoring our commitment to innovation, efficiency, and customer satisfaction. By integrating state-of-the-art technology with deep scientific understanding, Clovertex paves the way in optimizing the intersection of information technology and pharmaceutical development. ## Useful links 1. [J&J buys Intra-Cellular in $14.6 billion deal, delving further into central nervous system disorders](https://apnews.com/article/johnson-jnj-intracellular-schizophrenia-19160ba4559aaab40836078d12a89800) 2. Clovertex [website](http://clovertex.com) [Clovertex](https://cryoduck.com/blog/tag/clovertex), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month) ## Related posts [![dgc](https://cryoduck.com/hs-fs/hubfs/dgc.png?height=200&name=dgc.png)](https://cryoduck.com/blog/dgc) [Clovertex](https://cryoduck.com/blog/tag/clovertex), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month) ## [Clovertex Target of the Month (12/24): DGC](https://cryoduck.com/blog/dgc) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Jan 11, 2025 11:28:00 PM Clovertex’s December Target of the Month is the Dystrophin-Glycoprotein Complex (DGC), inspired by... [Read more](https://cryoduck.com/blog/dgc) [![gipr](https://cryoduck.com/hs-fs/hubfs/gipr.png?height=200&name=gipr.png)](https://cryoduck.com/blog/gipr) [Clovertex](https://cryoduck.com/blog/tag/clovertex), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month) ## [Clovertex Target of the Year 2024: GIPR](https://cryoduck.com/blog/gipr) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Jan 13, 2025 11:10:08 AM Clovertex’s Target of the Year 2024 is the Gastric Inhibitory Polypeptide Receptor (GIPR), which... [Read more](https://cryoduck.com/blog/gipr) [![hsa](https://cryoduck.com/hs-fs/hubfs/albumin.png?height=200&name=albumin.png)](https://cryoduck.com/blog/hsa) [Clovertex](https://cryoduck.com/blog/tag/clovertex), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month) ## [Clovertex Target of the Month (10/25): HSA](https://cryoduck.com/blog/hsa) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Nov 8, 2025 4:17:09 PM Clovertex’s October Target of the Month is human serum albumin, the body’s most abundant... 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