--- title: The cryoDuck Blog - Commentary on everything cryo-EM in drug discovery. | membrane protein description: membrane protein | Explore cryoDuck B.V.'s blog for the latest insights, news, and commentary in the world of cryo-EM and drug discovery. image: https://cryoduck.com/hubfs/4.png --- [Skip to content](https://cryoduck.com/blog/tag/membrane-protein#main-content) [![cryoDuck Logo](https://cryoduck.com/hs-fs/hubfs/Home/horizontal%20light%20bg.png?width=300&height=66&name=horizontal%20light%20bg.png)](https://cryoduck.com) - [Home](https://cryoduck.com/) - [About](https://cryoduck.com/about) - [Blog](https://cryoduck.com/blog) - [Newsletter](https://cryoduck.com/newsletter) Open main navigation Close main navigation - [Home](https://cryoduck.com/) - [About](https://cryoduck.com/about) - [Blog](https://cryoduck.com/blog) - [Newsletter](https://cryoduck.com/newsletter) - [Contact us](https://cryoduck.com/contact) [Contact us](https://cryoduck.com/contact) # The cryoDuck Blog Commentary on everything related to cryo-EM in drug discovery. [![her3](https://cryoduck.com/hubfs/M4R-target.png)](https://cryoduck.com/blog/m4r) [Clovertex](https://cryoduck.com/blog/tag/clovertex), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month), [membrane protein](https://cryoduck.com/blog/tag/membrane-protein) ## [Clovertex Target of the Month (12/23): M4R](https://cryoduck.com/blog/m4r) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Dec 31, 2023 4:42:21 PM Amidst a flurry of big pharma deals, the Muscarinic acetylcholine receptor subtype M4 has emerged as... [Read more](https://cryoduck.com/blog/m4r) [![her3](https://cryoduck.com/hubfs/FRalpha.png)](https://cryoduck.com/blog/fralpha) [Clovertex](https://cryoduck.com/blog/tag/clovertex), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month), [membrane protein](https://cryoduck.com/blog/tag/membrane-protein) ## [Clovertex Target of the Month (11/23): FRalpha](https://cryoduck.com/blog/fralpha) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Dec 1, 2023 12:35:14 AM This November, we highlight the folate receptor alpha (FRα) as the 'Clovertex Target of the Month'. ... [Read more](https://cryoduck.com/blog/fralpha) [![her3](https://cryoduck.com/hubfs/HER3.png)](https://cryoduck.com/blog/her3) [Clovertex](https://cryoduck.com/blog/tag/clovertex), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month), [membrane protein](https://cryoduck.com/blog/tag/membrane-protein) ## [Clovertex Target of the Month (10/23): HER3](https://cryoduck.com/blog/her3) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Oct 31, 2023 1:28:04 PM For October 2023, we have the Human Epidermal growth factor Receptor 3 (HER3) as the 'Clovertex Drug... [Read more](https://cryoduck.com/blog/her3) [![AAV9](https://cryoduck.com/hubfs/Target%20of%20the%20month-1.png)](https://cryoduck.com/blog/gpr61) [Clovertex](https://cryoduck.com/blog/tag/clovertex), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month), [membrane protein](https://cryoduck.com/blog/tag/membrane-protein) ## [Clovertex Target of the Month (09/23): GPR61](https://cryoduck.com/blog/gpr61) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Sep 30, 2023 6:46:15 PM September's Clovertex Target of the Month is GPR61 following Pfizer's recent publication concerning ... [Read more](https://cryoduck.com/blog/gpr61) [![AAV9](https://cryoduck.com/hubfs/Target%20of%20the%20month.png)](https://cryoduck.com/blog/gabaar) [Clovertex](https://cryoduck.com/blog/tag/clovertex), [target of the month](https://cryoduck.com/blog/tag/target-of-the-month), [membrane protein](https://cryoduck.com/blog/tag/membrane-protein) ## [Clovertex Target of the Month (08/23): GABAAR](https://cryoduck.com/blog/gabaar) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Aug 31, 2023 11:42:52 PM In August 2023, the GABAA receptor is highlighted our 'Clovertex Target of the Month' as the drug ta... [Read more](https://cryoduck.com/blog/gabaar) [![Ammunition](https://cryoduck.com/hubfs/Ammunition.png)](https://cryoduck.com/blog/ucp1) [cryo-EM in drug discovery](https://cryoduck.com/blog/tag/cryo-em-in-drug-discovery), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets), [membrane protein](https://cryoduck.com/blog/tag/membrane-protein), [small targets](https://cryoduck.com/blog/tag/small-targets) ## [32 kDa UCP1: Sybody-LEGOBody strategy puts the journey from munitions workers to weight loss drug target in cryo-EM crosshairs](https://cryoduck.com/blog/ucp1) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Jun 26, 2023 10:23:13 AM From the trenches of World War I to the ongoing battle against obesity, the story of UCP1 is as capt... 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