In a previous discussion, we highlighted the Manual Plunge Cooler by MiTeGen and its potential to connect more novices to the cryo-EM workflow. Now, we turn our attention to a key module of the Manual Plunge Cooler – the Ethane Cryostat, which was designed to make a novice's life easier. Importantly, while it integrates seamlessly with MiTeGen's Manual Plunge Cooler, it's also compatible with the widely-used ThermoFisher™ Vitrobot™.
For newcomers to cryo-EM, the process of liquifying and maintaining ethane in its liquid state is a daunting one. The Ethane Cryostat, with its meticulous temperature control, simplifies this aspect of the workflow. By ensuring that the ethane remains in a controlled state, the risks associated with freezing and potential tweezer damages are virtually eliminated. This serves as a confidence booster for trainees and reduces the time that facility managers need to devote to user training.
A noteworthy feature of the Ethane Cryostat is its compatibility not just with MiTeGen's Manual Plunge Cooler, but also with the ThermoFisher Vitrobot. Such versatility means that labs utilizing varied equipment can still benefit from the Ethane Cryostat's offerings. This encourages a more cohesive approach to cryo-EM training and research, strengthening collaborations.
It's often the nuanced challenges in scientific research that can become significant hurdles for practitioners. By addressing these intricacies, tools like the Ethane Cryostat make a tangible difference in the daily lives of those immersed in cryo-EM. MiTeGen's commitment to simplifying these complexities not only advances the field but also echoes the sentiments of many in the community: it's the finer details that often matter most. By focusing on these, we pave the way for a smoother, more efficient research landscape for all.
1. Learn more about the Manual Plunge Cooler and Temperature Controlled Ethane Cryostat.
2. MiTeGen website.