---
title: MiTeGen Hottest Tweets in SBDD (07/24)
description: MiTeGen Hottest Tweets in SBDD, your curated source of recent tweets for those who want to stay up to date with the fast-moving world of Cryo-EM Twitter.
image: https://cryoduck.com/hubfs/Glow.png
---

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 Jul 17, 2024 2:31:15 PM

# MiTeGen Hottest Tweets in SBDD (07/24)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia)

Share: [linkedin-in icon](http://www.linkedin.com/shareArticle?mini=true&url=https://cryoduck.com/blog/tweets-0724) [Twitter icon](https://twitter.com/intent/tweet?url=https://cryoduck.com/blog/tweets-0724) [envelope icon](mailto:?body=https://cryoduck.com/blog/tweets-0724)

Here are your [MiTeGen](http://www.mitegen.com) Hottest Tweets in SBDD with exciting software developments such as newly released EMHub or the latest SerialEM/EPU updates.

> Streamline your cryo-EM workflow with GridPrepBlock! This innovative tool securely holds up to 5 grids during plasma activation & other surface treatments. Medical grade aluminum, ergonomic design & easy tweezer access make grid prep a breeze. [#cryoEM](https://twitter.com/hashtag/cryoEM?src=hash&ref_src=twsrc%5Etfw) [https://t.co/fT4Ad6vQoq](https://t.co/fT4Ad6vQoq) [pic.twitter.com/XfOm5Y62nb](https://t.co/XfOm5Y62nb)
> 
> — MiTeGen (@MiTeGen) [July 1, 2024](https://twitter.com/MiTeGen/status/1807791279834829192?ref_src=twsrc%5Etfw)

## Tough drug targets

> Happy to share our latest work on cytoplasmic mRNA degradation by the Ski-exosome assembly. We reveal via SPA cryoEM how different conformational states of the Ski complex are connected to exosome recruitment and RNA handover. Thanks to everybody involved [@LabConti](https://twitter.com/LabConti?ref_src=twsrc%5Etfw) [@MPI\_Biochem](https://twitter.com/MPI_Biochem?ref_src=twsrc%5Etfw) [pic.twitter.com/mTDAlOeb2j](https://t.co/mTDAlOeb2j)
> 
> — Achim Keidel (@KeidelAchim) [October 25, 2023](https://twitter.com/KeidelAchim/status/1717110741386358922?ref_src=twsrc%5Etfw)

> Glad to present our latest results published today in [@Nature](https://twitter.com/Nature?ref_src=twsrc%5Etfw) revealing the activation mechanism of the AAA+-dependent IS21 transposase. Congrats to all the authors![@CIB\_CSIC](https://twitter.com/CIB_CSIC?ref_src=twsrc%5Etfw), [@CSIC](https://twitter.com/CSIC?ref_src=twsrc%5Etfw)
> 
> Full story here:[https://t.co/NMR2ASqP49](https://t.co/NMR2ASqP49)[https://t.co/SmX8i15Zwa](https://t.co/SmX8i15Zwa)
> 
> and brief summary below 👇🧵 [pic.twitter.com/2Hm3HTA7KA](https://t.co/2Hm3HTA7KA)
> 
> — Ernesto Arias-Palomo (@EAriasPalomo) [June 27, 2024](https://twitter.com/EAriasPalomo/status/1806199316932903319?ref_src=twsrc%5Etfw)

> Interesting: Cryo-EM structure of neurotensin receptor 1 in complex with beta-arrestin1 and SBI-553 (complex 3)[#gpcr](https://twitter.com/hashtag/gpcr?src=hash&ref_src=twsrc%5Etfw)[https://t.co/vS1L0qLUxN](https://t.co/vS1L0qLUxN)
> 
> — BryanRoth (@zenbrainest) [June 26, 2024](https://twitter.com/zenbrainest/status/1806074409872162853?ref_src=twsrc%5Etfw)

> The HIV Co-Receptor CCR5 active structure from our collaboration [https://t.co/upSt93TRze](https://t.co/upSt93TRze)
> 
> — Gebhard F X Schertler (@GSchertler) [June 26, 2024](https://twitter.com/GSchertler/status/1805863216754704399?ref_src=twsrc%5Etfw)

> In its final form out today: The complex structure of human tRNA methyltransferase METTL6 in complex with a fully modified serine tRNA and seryl-tRNA synthetase (SerRS). [https://t.co/MsAkh5PUWK](https://t.co/MsAkh5PUWK). All maps, models and micrographs are out as well! Some highlights: [pic.twitter.com/OF6wb0vs33](https://t.co/OF6wb0vs33)
> 
> — Eva Kowalinski (@KowaEva) [June 25, 2024](https://twitter.com/KowaEva/status/1805617606591758465?ref_src=twsrc%5Etfw)

> Very excited to share our latest paper! We solved the structure of the helper NLR NRC2 activated by the virus resistance protein Rx using cryo-EM. It forms a hexameric inflammasome-like resistosome!  
> 1/14[https://t.co/Om76TJ93XF](https://t.co/Om76TJ93XF) [pic.twitter.com/P8EJ2wXwNY](https://t.co/P8EJ2wXwNY)
> 
> — Jogi Madhuprakash (@JMadhuprakash) [June 20, 2024](https://twitter.com/JMadhuprakash/status/1803750339432124901?ref_src=twsrc%5Etfw)

## The weird and wonderful

> Our manuscript  
> High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles  
> is now published in Science![https://t.co/NUWTFo84Ch](https://t.co/NUWTFo84Ch) [pic.twitter.com/G1S3FyAdV1](https://t.co/G1S3FyAdV1)
> 
> — John Rubinstein (@RubinsteinJohn) [June 20, 2024](https://twitter.com/RubinsteinJohn/status/1803858953756885146?ref_src=twsrc%5Etfw)

> 2D classes of a few particles from a contaminant on our sample, am I the only one seeing evil ? 🤣 [#cryoemcanbefun](https://twitter.com/hashtag/cryoemcanbefun?src=hash&ref_src=twsrc%5Etfw) [@unimelb](https://twitter.com/UniMelb?ref_src=twsrc%5Etfw) [@Bio21Institute](https://twitter.com/Bio21Institute?ref_src=twsrc%5Etfw) [pic.twitter.com/jZ1Gzdpxp6](https://t.co/jZ1Gzdpxp6)
> 
> — Eric Hanssen (@big\_french\_man) [June 17, 2024](https://twitter.com/big_french_man/status/1802527852686156194?ref_src=twsrc%5Etfw)

## Sample preparation

> Getting ready to start [#ACA2024](https://twitter.com/hashtag/ACA2024?src=hash&ref_src=twsrc%5Etfw) with Craig Yoshioka by leading WK-3: Hands-on CryoEM Sample Preparation & Data Collection Workshop Using [#CryoEM](https://twitter.com/hashtag/CryoEM?src=hash&ref_src=twsrc%5Etfw) Merit Badges.
> 
> We thank our sponsors [@NanoSoftCryoEM](https://twitter.com/NanoSoftCryoEM?ref_src=twsrc%5Etfw) [@altos\_labs](https://twitter.com/altos_labs?ref_src=twsrc%5Etfw) [@thermosciEMSpec](https://twitter.com/thermosciEMSpec?ref_src=twsrc%5Etfw) [@MiTeGen](https://twitter.com/MiTeGen?ref_src=twsrc%5Etfw) & the CryoEM/Service SIGs for their support. [https://t.co/W1ocz7ahpB](https://t.co/W1ocz7ahpB) [pic.twitter.com/9PrgCgybDF](https://t.co/9PrgCgybDF)
> 
> — Edward T Eng (@edward\_eng) [July 7, 2024](https://twitter.com/edward_eng/status/1809952786504622390?ref_src=twsrc%5Etfw)

> Have you visited the MiTeGen booth #313 at the ACA Annual meeting yet? You'll find an array of our [#cryoem](https://twitter.com/hashtag/cryoem?src=hash&ref_src=twsrc%5Etfw) & [#crystallography](https://twitter.com/hashtag/crystallography?src=hash&ref_src=twsrc%5Etfw) tools & instruments. This includes the manual plunge cooler & cryostat [https://t.co/gsH6pgm7gl](https://t.co/gsH6pgm7gl) - Watershed [https://t.co/xxh1iOtPus](https://t.co/xxh1iOtPus) & much more [#aca2024](https://twitter.com/hashtag/aca2024?src=hash&ref_src=twsrc%5Etfw) [pic.twitter.com/yq5ksNOVW7](https://t.co/yq5ksNOVW7)
> 
> — MiTeGen (@MiTeGen) [July 9, 2024](https://twitter.com/MiTeGen/status/1810788522200277041?ref_src=twsrc%5Etfw)

## Better imaging

> Smart EPU 3.8 is a big release!  
> ✅️ plasmon imaging  
> ✅️ full support for tilted acquisition  
> ✅️ ice thickness prediction for the selection of foil holes during screening
> 
> Visit Smart EPU YouTube channel to learn about the new features:[https://t.co/LX5wdFhztx](https://t.co/LX5wdFhztx)
> 
> — Ieva Drulyte (@IevaDrulyte) [June 21, 2024](https://twitter.com/IevaDrulyte/status/1804077594469396909?ref_src=twsrc%5Etfw)

> Last week's release of [#SerialEM](https://twitter.com/hashtag/SerialEM?src=hash&ref_src=twsrc%5Etfw) beta testing introduces "Multiple Grid Ops", an interface to auto acquire grid maps, square maps, and final data from multiple grids in a row using [@thermosciEMSpec](https://twitter.com/thermosciEMSpec?ref_src=twsrc%5Etfw) /[@JEOLUSA](https://twitter.com/JEOLUSA?ref_src=twsrc%5Etfw) autoloaders. [pic.twitter.com/6besZUhqug](https://t.co/6besZUhqug)
> 
> — Guenter Resch (@Nexperion) [June 18, 2024](https://twitter.com/Nexperion/status/1802982363124633613?ref_src=twsrc%5Etfw)

> Dear [#cryoem](https://twitter.com/hashtag/cryoem?src=hash&ref_src=twsrc%5Etfw) comrades. Check out our preprint on how 100 keV detectors help breathe fresh life into ubiquitously available LaB6-based TEM workhorses. A collaboration with [@GatanMicroscopy](https://twitter.com/GatanMicroscopy?ref_src=twsrc%5Etfw), [@GeorgRamm](https://twitter.com/GeorgRamm?ref_src=twsrc%5Etfw), and [@CryoEM\_Monash](https://twitter.com/CryoEM_Monash?ref_src=twsrc%5Etfw). [https://t.co/NOo13IZtqN](https://t.co/NOo13IZtqN)
> 
> — Hari Venugopal (@HariVenugopal2) [May 28, 2024](https://twitter.com/HariVenugopal2/status/1795289062976409955?ref_src=twsrc%5Etfw)

## Processing and IT

> Crafted with ❤️ for the scientific community and totally open-source! Don't hesitate to get in contact. [https://t.co/q7yvPGXAxb](https://t.co/q7yvPGXAxb)
> 
> — JM de la Rosa Trevin (@delarosatrevin) [July 16, 2024](https://twitter.com/delarosatrevin/status/1813243746814726330?ref_src=twsrc%5Etfw)

> For the rest of the world, there is this [pic.twitter.com/9fJiHJRsM3](https://t.co/9fJiHJRsM3)
> 
> — Dimitry Tegunov (@DTegunov) [July 5, 2024](https://twitter.com/DTegunov/status/1809084857651450195?ref_src=twsrc%5Etfw)

> New paper out in bioarxiv!. In collaboration with the team of Maks Ovsjanikov, Vincent Mallet developed an algorithm that is available as a plug-in for [@UCSFChimeraX](https://twitter.com/UCSFChimeraX?ref_src=twsrc%5Etfw) to find antibodies and nanobodies, within seconds, in [#cryoem](https://twitter.com/hashtag/cryoem?src=hash&ref_src=twsrc%5Etfw) densities. [https://t.co/7wR2FIjxdN](https://t.co/7wR2FIjxdN). Try it out!
> 
> — Chiara Rapisarda (@chiara\_rapi) [May 19, 2024](https://twitter.com/chiara_rapi/status/1792107456027349255?ref_src=twsrc%5Etfw)

## Thoughts and opinions

> Anonymous "likes" enable fake likes. This can simulate engagement that encourages users to create content & stay online (increasing the value of X), and can also adjust behaviour by rewarding specific messages.  
> Now even the echos in the echo chamber aren't necessarily real.
> 
> — John Rubinstein (@RubinsteinJohn) [June 13, 2024](https://twitter.com/RubinsteinJohn/status/1801271652862312462?ref_src=twsrc%5Etfw)

## Biotech news and drug discovery technologies

> Wow--mind blown!  
> "Computational design of soluble and functional membrane protein analogues"[@BShoichet](https://twitter.com/BShoichet?ref_src=twsrc%5Etfw) [@RothLabUNC](https://twitter.com/RothLabUNC?ref_src=twsrc%5Etfw) [https://t.co/o6xRH3LixM](https://t.co/o6xRH3LixM) [pic.twitter.com/5fv0vOifh0](https://t.co/5fv0vOifh0)
> 
> — BryanRoth (@zenbrainest) [June 19, 2024](https://twitter.com/zenbrainest/status/1803474677991612636?ref_src=twsrc%5Etfw)

> My experience with [#alphafold3](https://twitter.com/hashtag/alphafold3?src=hash&ref_src=twsrc%5Etfw) after determining the [#cryoEM](https://twitter.com/hashtag/cryoEM?src=hash&ref_src=twsrc%5Etfw) structures of he [#CRISPR](https://twitter.com/hashtag/CRISPR?src=hash&ref_src=twsrc%5Etfw) associated transposon complex,  
> we tested [#alphafold3](https://twitter.com/hashtag/alphafold3?src=hash&ref_src=twsrc%5Etfw) in this complex (1/9)
> 
> CheckMolecular Cell 👇
> 
> [https://t.co/vGEKFU4U7l](https://t.co/vGEKFU4U7l)
> 
> and [@proteofrankie](https://twitter.com/ProteoFrankie?ref_src=twsrc%5Etfw) tweetorial[https://t.co/iFOKuUYm2W](https://t.co/iFOKuUYm2W) [pic.twitter.com/QGN9g507BW](https://t.co/QGN9g507BW)
> 
> — Guillermo Montoya (@g1\_guillermo) [June 15, 2024](https://twitter.com/g1_guillermo/status/1801896005211738619?ref_src=twsrc%5Etfw)

## Ozemphoria

> Another snapshot of GLP-1 medicine use in the real world highlights the persistence adherence problem in people with chronic cardiometabolic disorders. New solutions are needed to achieve better outcomes [#T2D](https://twitter.com/hashtag/T2D?src=hash&ref_src=twsrc%5Etfw) [#Obesity](https://twitter.com/hashtag/Obesity?src=hash&ref_src=twsrc%5Etfw) [https://t.co/6cglfwCrYv](https://t.co/6cglfwCrYv)
> 
> — Daniel J Drucker (@DanielJDrucker) [July 10, 2024](https://twitter.com/DanielJDrucker/status/1811155130001101079?ref_src=twsrc%5Etfw)

> Weight loss drugs are the new iPhone [pic.twitter.com/bgRM29P6nq](https://t.co/bgRM29P6nq)
> 
> — Dare Obasanjo🐀 (@Carnage4Life) [June 29, 2024](https://twitter.com/Carnage4Life/status/1807105947980177877?ref_src=twsrc%5Etfw)

> Just published [@NEJM](https://twitter.com/NEJM?ref_src=twsrc%5Etfw)  
> Tirzepatide (GLP-1) clicks for protection vs sleep apnea in 2 randomized placebo-controlled trials: less symptoms, hypoxia, systolic BP, and reduction of inflammation by hs-CRP (w/ or w/o CPAP)[https://t.co/gy0iCjS7X8](https://t.co/gy0iCjS7X8) [@AtulMalhotra13](https://twitter.com/AtulMalhotra13?ref_src=twsrc%5Etfw) [#ADA2024](https://twitter.com/hashtag/ADA2024?src=hash&ref_src=twsrc%5Etfw) [pic.twitter.com/3H6QON8RGy](https://t.co/3H6QON8RGy)
> 
> — Eric Topol (@EricTopol) [June 21, 2024](https://twitter.com/EricTopol/status/1804259028278874215?ref_src=twsrc%5Etfw)

> Here the authors put forward the case for tirzepatide and GIP act directly in adipocytes to influence adipose tissue metabolism [@Cell\_Metabolism](https://twitter.com/Cell_Metabolism?ref_src=twsrc%5Etfw) [https://t.co/W5Wlo3ONN2](https://t.co/W5Wlo3ONN2)
> 
> — Daniel J Drucker (@DanielJDrucker) [June 15, 2024](https://twitter.com/DanielJDrucker/status/1801981950523015342?ref_src=twsrc%5Etfw)

> Eli Lilly CEO Dave Ricks says on [@WSJ](https://twitter.com/WSJ?ref_src=twsrc%5Etfw) podcast that the company probably needs "10 or 15" plants to "even approach" tirzepatide demand, each of which takes 3-4 years to get up and running. They're building 6 now: [https://t.co/dS9hAdjxN9](https://t.co/dS9hAdjxN9)
> 
> — Meg Tirrell (@megtirrell) [June 12, 2024](https://twitter.com/megtirrell/status/1800682310121173451?ref_src=twsrc%5Etfw)

> Is there a link between Semaglutide and erectile dysfunction? [https://t.co/IXIc0kURI1](https://t.co/IXIc0kURI1)
> 
> — Daniel J Drucker (@DanielJDrucker) [May 22, 2024](https://twitter.com/DanielJDrucker/status/1793222680486834467?ref_src=twsrc%5Etfw)

## About MiTeGen

MiTeGen, founded in 2004 by Cornell University Professor Robert Thorne, is a leading provider of innovative technologies for cryo-EM, crystallography, and other techniques used for probing small molecule and biomolecular structure and function. Our mission is to support researchers in achieving the best possible results throughout the entire process, from sample preparation to data collection.

With a strong emphasis on collaboration, we actively work with academic, government, and industrial researchers in over 40 countries to develop and deliver new tools and methods. Our products have gained recognition and trust within the scientific community, as they have been cited in over 4,500 published research articles. By leveraging concepts and technologies from physics and related fields, we tackle practical challenges faced by our friends and collaborators in the life sciences and other disciplines.

Driven by a passion for cryo cooling, we would like to showcase three of our innovative cryo-EM solutions:

[Manual Plunge Cooler and Precision Ethane Cryostat:](https://www.mitegen.com/product/manual-plunger-cooler-and-precision-cryostat/)

Our Manual Plunge Cooler and Precision Cryostat are specifically designed to streamline and optimize your cryo-EM sample vitrification workflow. These systems consist of three components that can be obtained individually or as a complete package, ensuring efficient and successful sample preparation.

[Cryo-EM Starter Kits:](https://www.mitegen.com/product-category/cryo-em/cryo-em-starter-kits/)

Our Cryo-EM starter kits are curated to equip your laboratory with all the necessary tools conveniently packaged together. These kits are ideal for labs aiming to perform basic grid and sample preparation for cryo-EM within their own facility, even on a reduced budget. The kit includes components essential for cryo-EM sample preparation, as well as sample storage and transport solutions.

[Cryo-EM AutoGrid Cassette Puck:](https://www.mitegen.com/product/cryoem-autogrid-cassette-puck/)

Our latest addition, the Cryo-EM AutoGrid Cassette Storage and Shipping puck, builds upon the success of our 2nd generation Cryo-EM Puck. This innovative solution allows users to screen samples on a instrument and seamlessly ship the same AutoGrid cassette puck to a collection facility. It also serves as a convenient storage option for facilities, enabling them to store their cassettes in the puck canes designed to fit into cassette loading stations.

These cryo-EM solutions exemplify our dedication to enhancing cryo cooling capabilities and simplifying workflows in the field of cryo-EM. MiTeGen continues to push the boundaries of innovation, enabling researchers to advance their structural biology studies with greater ease and efficiency.

[Contact us at MiTeGen](https://www.mitegen.com/booth/) today to arrange a no obligation consultation to learn how we can help you with your research.

[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## Related posts

[![](https://cryoduck.com/hs-fs/hubfs/kits.png?height=200&name=kits.png)](https://cryoduck.com/blog/tweets-0424)

[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## [MiTeGen Hottest Tweets in SBDD (04/24)](https://cryoduck.com/blog/tweets-0424)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Apr 19, 2024 10:00:57 PM

Here are your MiTeGen Hottest Tweets in SBDD, featuring heated discussions about the Inflation...

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[![](https://cryoduck.com/hs-fs/hubfs/Hottest%20tweets-2-1.png?height=200&name=Hottest%20tweets-2-1.png)](https://cryoduck.com/blog/tweets-0723)

[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## [MiTeGen Hottest Tweets in SBDD (07/23)](https://cryoduck.com/blog/tweets-0723)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Jul 15, 2023 10:11:01 PM

Here are your MiTeGen Hottest Tweets in SBDD, showcasing incredibly beautiful structures of...

[Read more](https://cryoduck.com/blog/tweets-0723)

[![](https://cryoduck.com/hs-fs/hubfs/Hottest%20tweets-Nov-26-2023-01-17-30-5274-PM.png?height=200&name=Hottest%20tweets-Nov-26-2023-01-17-30-5274-PM.png)](https://cryoduck.com/blog/tweets-1123)

[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## [MiTeGen Hottest Tweets in SBDD (11/23)](https://cryoduck.com/blog/tweets-1123)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

 Nov 26, 2023 2:17:38 PM

This month's your MiTeGen Hottest Tweets in SBDD come with highlights across all topics including...

[Read more](https://cryoduck.com/blog/tweets-1123)

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