--- title: MiTeGen Hottest Tweets in SBDD (12/24) description: MiTeGen Hottest Tweets in SBDD, your curated source of recent tweets for those who want to stay up to date with the fast-moving world of Cryo-EM Twitter. image: https://cryoduck.com/hubfs/Hottest%20tweets-2-1.png --- [Skip to content](https://cryoduck.com/blog/tweets-1224#main-content) [![cryoDuck Logo](https://cryoduck.com/hs-fs/hubfs/Home/horizontal%20light%20bg.png?width=300&height=66&name=horizontal%20light%20bg.png)](https://cryoduck.com) - [Home](https://cryoduck.com/) - [About](https://cryoduck.com/about) - [Blog](https://cryoduck.com/blog) - [Newsletter](https://cryoduck.com/newsletter) Open main navigation Close main navigation - [Home](https://cryoduck.com/) - [About](https://cryoduck.com/about) - [Blog](https://cryoduck.com/blog) - [Newsletter](https://cryoduck.com/newsletter) - [Contact us](https://cryoduck.com/contact) [Contact us](https://cryoduck.com/contact) Dec 21, 2024 10:08:32 AM # MiTeGen Hottest Tweets in SBDD (12/24) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Share: [linkedin-in icon](http://www.linkedin.com/shareArticle?mini=true&url=https://cryoduck.com/blog/tweets-1224) [Twitter icon](https://twitter.com/intent/tweet?url=https://cryoduck.com/blog/tweets-1224) [envelope icon](mailto:?body=https://cryoduck.com/blog/tweets-1224) Here are your [MiTeGen](http://www.mitegen.com) Hottest Tweets in SBDD, with mesmerizing protein machinery structures and algorithms that recognize side chains even in medium resolution maps: ## Tough drug targets > Native DGC structure rationalizes muscular dystrophy-causing mutations | Nature[https://t.co/hbzEyj4BbM](https://t.co/hbzEyj4BbM) [pic.twitter.com/FCgqvsfcdd](https://t.co/FCgqvsfcdd) > > — Membrane Protein PDB (@MemProtPDB) [December 11, 2024](https://twitter.com/MemProtPDB/status/1866944752266121521?ref_src=twsrc%5Etfw) > How NINJ1 mediates plasma membrane rupture and why NINJ2 cannot | Cell [https://t.co/JEL7oco4GH](https://t.co/JEL7oco4GH) [pic.twitter.com/ftHJbMmA1K](https://t.co/ftHJbMmA1K) > > — Membrane Protein PDB (@MemProtPDB) [December 11, 2024](https://twitter.com/MemProtPDB/status/1866946282117570760?ref_src=twsrc%5Etfw) > Molecular insights into the activation mechanism of GPR156 in maintaining auditory function | Nat Commun[https://t.co/nCgDkn7q9o](https://t.co/nCgDkn7q9o) [pic.twitter.com/HG8j1h2xt5](https://t.co/HG8j1h2xt5) > > — Membrane Protein PDB (@MemProtPDB) [December 9, 2024](https://twitter.com/MemProtPDB/status/1865998892245848327?ref_src=twsrc%5Etfw) > 🚨Paper alarm > Our new work on APC/C regulation revealed by high resolution cryo-EM structures together with the groups of Leifu Chang and David Barford has been published [@NatureComms](https://twitter.com/NatureComms?ref_src=twsrc%5Etfw). Congratulations to Anna Höfler, Jun Yu and all other authors. > 🔗[https://t.co/cWizTIaTNx](https://t.co/cWizTIaTNx) [pic.twitter.com/JSJjoAXdFA](https://t.co/JSJjoAXdFA) > > — Andreas Boland (@BolandLab\_GE) [November 21, 2024](https://twitter.com/BolandLab_GE/status/1859508976590713147?ref_src=twsrc%5Etfw) ## The weird and wonderful > Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of [@MarkertJon](https://twitter.com/MarkertJon?ref_src=twsrc%5Etfw) [https://t.co/g27t5Rw5RY](https://t.co/g27t5Rw5RY) [pic.twitter.com/zUoAC31ML9](https://t.co/zUoAC31ML9) > > — Lucas Farnung (@LucasFarnung) [December 12, 2024](https://twitter.com/LucasFarnung/status/1867288697852547159?ref_src=twsrc%5Etfw) ## Sample preparation > Molecular architecture of synaptic vesicles | PNAS[https://t.co/VjbyNEucZV](https://t.co/VjbyNEucZV) [pic.twitter.com/5X1Suyi0sy](https://t.co/5X1Suyi0sy) > > — Membrane Protein PDB (@MemProtPDB) [November 27, 2024](https://twitter.com/MemProtPDB/status/1861853235503661257?ref_src=twsrc%5Etfw) ## Better imaging > SPACEtomo v1.2 is online! [https://t.co/3GO6qP9Z07](https://t.co/3GO6qP9Z07) > > - Improved GUIs for lamella detection, target selection and CLEM registration make it the best target selection workflow for PACEtomo on any kind of lamella sample. > - Easier installation and configuration > Any feedback welcome! [pic.twitter.com/j29H4LmlD2](https://t.co/j29H4LmlD2) > > — Fabian (@EisFabian) [December 17, 2024](https://twitter.com/EisFabian/status/1868949582463558071?ref_src=twsrc%5Etfw) ## Processing and IT > "Recognizing amino acid sidechains in a medium resolution cryo-electron density map"[https://t.co/3pXht18oBQ](https://t.co/3pXht18oBQ) > > — Andreas Boland (@BolandLab\_GE) [December 16, 2024](https://twitter.com/BolandLab_GE/status/1868699908418814080?ref_src=twsrc%5Etfw) > Our experience with [#alphafold3](https://twitter.com/hashtag/alphafold3?src=hash&ref_src=twsrc%5Etfw) 🤖 (code recently released) and some of our most recent [#cryoEM](https://twitter.com/hashtag/cryoEM?src=hash&ref_src=twsrc%5Etfw) 🔬 structures (thread below) [https://t.co/SmX8i15Zwa](https://t.co/SmX8i15Zwa)[https://t.co/hwJUlkwhye](https://t.co/hwJUlkwhye) [pic.twitter.com/vIc8ae5ubV](https://t.co/vIc8ae5ubV) > > — Ernesto Arias-Palomo (@EAriasPalomo) [November 25, 2024](https://twitter.com/EAriasPalomo/status/1861014976720204191?ref_src=twsrc%5Etfw) ## Thoughts and opinions > Atlas XIV - our new $450M fund - and Reflections On The VC Math Problem [https://t.co/xh4ZgjOMSZ](https://t.co/xh4ZgjOMSZ) > > — Bruce Booth (@LifeSciVC) [December 5, 2024](https://twitter.com/LifeSciVC/status/1864645281893036157?ref_src=twsrc%5Etfw) > Sorry Oli, I no longer comment on science on this platform. That has now moved to [@bluesky](https://twitter.com/bluesky?ref_src=twsrc%5Etfw). > > — Sjors Scheres (@SjorsScheres) [December 5, 2024](https://twitter.com/SjorsScheres/status/1864759112153669949?ref_src=twsrc%5Etfw) ## Biotech news and drug discovery technologies > Would you like to discover low-efficacy ligands or biased ligands for GPCRs? Our fine-tuned deep learning models using transfer learning and protein language processing make it possible! | bioRxiv [https://t.co/3QeLZ3VZK3](https://t.co/3QeLZ3VZK3) > > — Marta Filizola (@martafilizola) [December 11, 2024](https://twitter.com/martafilizola/status/1866818817562747099?ref_src=twsrc%5Etfw) > This is one of the most amazing technologies I've seen--when I saw the [@biorxivpreprint](https://twitter.com/biorxivpreprint?ref_src=twsrc%5Etfw) paper I thought: "Wow why didn't I think of that?!" [https://t.co/78znsrtkOb](https://t.co/78znsrtkOb) > > — BryanRoth (@zenbrainest) [December 4, 2024](https://twitter.com/zenbrainest/status/1864359660314349991?ref_src=twsrc%5Etfw) ## Ozemphoria > Chart below kind of supports the thesis that GLP-1s will replace lipid based MASH therapeutics before they arrive. F4 anti-fibrotics still very much in play even if GLPs dominate the early F1-F3 space….[$MDGL](https://twitter.com/search?q=%24MDGL&src=ctag&ref_src=twsrc%5Etfw) is NOT dead on arrival imo - there is still time and room to play… [https://t.co/ABMOUyhKOa](https://t.co/ABMOUyhKOa) > > — BowTiedBiotech 🧪🔬🧬 (@BowTiedBiotech) [December 16, 2024](https://twitter.com/BowTiedBiotech/status/1868469822540960054?ref_src=twsrc%5Etfw) ## About MiTeGen MiTeGen, founded in 2004 by Cornell University Professor Robert Thorne, is a leading provider of innovative technologies for cryo-EM, crystallography, and other techniques used for probing small molecule and biomolecular structure and function. Our mission is to support researchers in achieving the best possible results throughout the entire process, from sample preparation to data collection. With a strong emphasis on collaboration, we actively work with academic, government, and industrial researchers in over 40 countries to develop and deliver new tools and methods. Our products have gained recognition and trust within the scientific community, as they have been cited in over 4,500 published research articles. By leveraging concepts and technologies from physics and related fields, we tackle practical challenges faced by our friends and collaborators in the life sciences and other disciplines. Driven by a passion for cryo cooling, we would like to showcase three of our innovative cryo-EM solutions: [Manual Plunge Cooler and Precision Ethane Cryostat:](https://www.mitegen.com/product/manual-plunger-cooler-and-precision-cryostat/) Our Manual Plunge Cooler and Precision Cryostat are specifically designed to streamline and optimize your cryo-EM sample vitrification workflow. These systems consist of three components that can be obtained individually or as a complete package, ensuring efficient and successful sample preparation. [Cryo-EM Starter Kits:](https://www.mitegen.com/product-category/cryo-em/cryo-em-starter-kits/) Our Cryo-EM starter kits are curated to equip your laboratory with all the necessary tools conveniently packaged together. These kits are ideal for labs aiming to perform basic grid and sample preparation for cryo-EM within their own facility, even on a reduced budget. The kit includes components essential for cryo-EM sample preparation, as well as sample storage and transport solutions. [Cryo-EM AutoGrid Cassette Puck:](https://www.mitegen.com/product/cryoem-autogrid-cassette-puck/) Our latest addition, the Cryo-EM AutoGrid Cassette Storage and Shipping puck, builds upon the success of our 2nd generation Cryo-EM Puck. This innovative solution allows users to screen samples on a instrument and seamlessly ship the same AutoGrid cassette puck to a collection facility. It also serves as a convenient storage option for facilities, enabling them to store their cassettes in the puck canes designed to fit into cassette loading stations. These cryo-EM solutions exemplify our dedication to enhancing cryo cooling capabilities and simplifying workflows in the field of cryo-EM. MiTeGen continues to push the boundaries of innovation, enabling researchers to advance their structural biology studies with greater ease and efficiency. [Contact us at MiTeGen](https://www.mitegen.com/booth/) today to arrange a no obligation consultation to learn how we can help you with your research. [MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets) ## Related posts [![](https://cryoduck.com/hs-fs/hubfs/Hottest%20tweets-2-1.png?height=200&name=Hottest%20tweets-2-1.png)](https://cryoduck.com/blog/tweets-1024) [MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets) ## [MiTeGen Hottest Tweets in SBDD (10/24)](https://cryoduck.com/blog/tweets-1024) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Oct 20, 2024 10:23:07 PM Here are your MiTeGen Hottest Tweets in SBDD, with tweets coming in in wake of Nobel Prize with... [Read more](https://cryoduck.com/blog/tweets-1024) [![](https://cryoduck.com/hs-fs/hubfs/Hottest%20tweets-2-1.png?height=200&name=Hottest%20tweets-2-1.png)](https://cryoduck.com/blog/tweets-1124) [MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets) ## [MiTeGen Hottest Tweets in SBDD (11/24)](https://cryoduck.com/blog/tweets-1124) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Nov 26, 2024 10:01:09 AM Here are your MiTeGen Hottest Tweets in SBDD, showcasing how laser flash melting might... [Read more](https://cryoduck.com/blog/tweets-1124) [![](https://cryoduck.com/hs-fs/hubfs/kits.png?height=200&name=kits.png)](https://cryoduck.com/blog/tweets-0424) [MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets) ## [MiTeGen Hottest Tweets in SBDD (04/24)](https://cryoduck.com/blog/tweets-0424) ![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) Apr 19, 2024 10:00:57 PM Here are your MiTeGen Hottest Tweets in SBDD, featuring heated discussions about the Inflation... 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