---
title: MiTeGen Hottest Tweets in SBDD (08/23)
description: MiTeGen Hottest Tweets in SBDD, your curated source of recent tweets for those who want to stay up to date with the fast-moving world of Cryo-EM Twitter.
image: https://cryoduck.com/hubfs/Hottest%20tweets-1.png
---

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 Aug 15, 2023 3:31:59 PM

# MiTeGen Hottest Tweets in SBDD (08/23)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia)

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In this edition of [MiTeGen](http://www.mitegen.com) Hottest Tweets in SBDD, the biotech world is manic about incretin mimetics, while the cryo-EM community nostalgically longs for FSC resolution cutoffs. Also check out this cool Ethane Cryostat for ethane temperature control on your Vitrobot:

> Our NEW Ethane Cryostat for the MiTeGen Manual Plunge Cooler [https://t.co/CFRKMvKKbX](https://t.co/CFRKMvKKbX) or Vitrobot: temp-controlled liquid ethane for user-friendly vitrification, reducing risks to your samples and equipment - Learn More [https://t.co/4gtksZ6beX](https://t.co/4gtksZ6beX) [#cryoem](https://twitter.com/hashtag/cryoem?src=hash&ref_src=twsrc%5Etfw) [pic.twitter.com/ipGYVMvsPo](https://t.co/ipGYVMvsPo)
> 
> — MiTeGen (@MiTeGen) [July 25, 2023](https://twitter.com/MiTeGen/status/1683673429931880448?ref_src=twsrc%5Etfw)

## Tough drug targets

> Our new [@ACSBioMed](https://twitter.com/ACSBioMed?ref_src=twsrc%5Etfw) JMedChem is out in ASAPs describing the discovery of our [#PfizerChemistry](https://twitter.com/hashtag/PfizerChemistry?src=hash&ref_src=twsrc%5Etfw) small molecule orally-active GLP1 agonist. Thank you to a great team from so many disciplines that made this possible[https://t.co/5JEi2ZTuvk](https://t.co/5JEi2ZTuvk)
> 
> — Scott Bagley (@BagPhos) [June 1, 2022](https://twitter.com/BagPhos/status/1531996358412013569?ref_src=twsrc%5Etfw)

> Tail engagement of arrestin at the glucagon receptor[https://t.co/JtVFiTiDvM](https://t.co/JtVFiTiDvM)
> 
> — Cheers (@raintank2010) [August 10, 2023](https://twitter.com/raintank2010/status/1689507582095011840?ref_src=twsrc%5Etfw)

> new release2
> 
> 8JPB: NTSR1-GRK2-Gαq complexes 1  
> 8JPC: NTSR1-GRK2-Gαq complexes 2
> 
> Focused refinement structure of  
> 8JPD: GRK2  
> 8JPE: Gαq  
> 8JPF: NTSR1  
> in NTSR1-GRK2-Gαq complexes
> 
> "GPCR activation and GRK2 assembly by a biased intracellular agonist."
> 
> Xu lab. Nature. [pic.twitter.com/4rSEUdHbvI](https://t.co/4rSEUdHbvI)
> 
> — Hideaki E. Kato (@emeKato) [August 9, 2023](https://twitter.com/emeKato/status/1689211673243271169?ref_src=twsrc%5Etfw)

> Here, high-resolution [#cryoEM](https://twitter.com/hashtag/cryoEM?src=hash&ref_src=twsrc%5Etfw) structures help pave the way to facilitate rational drug design of novel and optimized Prostaglandin F2α Receptor-targeting drugs. Congrats to the Chinese Academy of Sciences Shanghai for these fantastic results! [https://t.co/3SYXjuXygq](https://t.co/3SYXjuXygq)
> 
> — Ieva Drulyte (@IevaDrulyte) [August 9, 2023](https://twitter.com/IevaDrulyte/status/1689162359237971968?ref_src=twsrc%5Etfw)

> Mitochondrial stress causes DELE1 to form a large signaling scaffold that activates the integrated stress response. Congrats [@\_JieYang](https://twitter.com/_JieYang?ref_src=twsrc%5Etfw) for initiating this project several years ago, and our amazing collaborators in the [@LabWiseman](https://twitter.com/LabWiseman?ref_src=twsrc%5Etfw) and [@KampmannLab](https://twitter.com/KampmannLab?ref_src=twsrc%5Etfw) labs! [https://t.co/pqzZrB7dKz](https://t.co/pqzZrB7dKz) [pic.twitter.com/d0HHrzBN03](https://t.co/d0HHrzBN03)
> 
> — Lander Lab (@LanderLab) [August 7, 2023](https://twitter.com/LanderLab/status/1688594088839536640?ref_src=twsrc%5Etfw)

> Mitochondrial stress causes DELE1 to form a large signaling scaffold that activates the integrated stress response. Congrats [@\_JieYang](https://twitter.com/_JieYang?ref_src=twsrc%5Etfw) for initiating this project several years ago, and our amazing collaborators in the [@LabWiseman](https://twitter.com/LabWiseman?ref_src=twsrc%5Etfw) and [@KampmannLab](https://twitter.com/KampmannLab?ref_src=twsrc%5Etfw) labs! [https://t.co/pqzZrB7dKz](https://t.co/pqzZrB7dKz) [pic.twitter.com/d0HHrzBN03](https://t.co/d0HHrzBN03)
> 
> — Lander Lab (@LanderLab) [August 7, 2023](https://twitter.com/LanderLab/status/1688594088839536640?ref_src=twsrc%5Etfw)

> A cancer vaccine is delivered to the lung by an engineered attenuated influenza virus [https://t.co/Wm1UW9S2xe](https://t.co/Wm1UW9S2xe)
> 
> — Nature Biotechnology (@NatureBiotech) [August 8, 2023](https://twitter.com/NatureBiotech/status/1688727980414013440?ref_src=twsrc%5Etfw)

> Targeted lipid modification may provide a single intervention strategy for design of long-acting, nonselective, Amylin-based DACRAs with potential anti- [#obesity](https://twitter.com/hashtag/obesity?src=hash&ref_src=twsrc%5Etfw) effects [@nchembio](https://twitter.com/nchembio?ref_src=twsrc%5Etfw) [https://t.co/lodxvRLa7I](https://t.co/lodxvRLa7I)
> 
> — Daniel J Drucker (@DanielJDrucker) [August 4, 2023](https://twitter.com/DanielJDrucker/status/1687513799144722447?ref_src=twsrc%5Etfw)

> Not super sure when is best to tweet in the new [@eLife](https://twitter.com/eLife?ref_src=twsrc%5Etfw) process, and I probably missed the boat 😅, but out today is the "version of record" for our work on the regulation of membrane receptor guanylyl cyclases. (1/3) [https://t.co/1fjVkk3FFy](https://t.co/1fjVkk3FFy) [pic.twitter.com/hxHCI8IzF2](https://t.co/hxHCI8IzF2)
> 
> — Nathanael Caveney (@CaveneyNA) [August 3, 2023](https://twitter.com/CaveneyNA/status/1687185304539762688?ref_src=twsrc%5Etfw)

> [#CryoEM](https://twitter.com/hashtag/CryoEM?src=hash&ref_src=twsrc%5Etfw) structures by [@DianaArseni](https://twitter.com/DianaArseni?ref_src=twsrc%5Etfw) in [@bwfalcon](https://twitter.com/bwfalcon?ref_src=twsrc%5Etfw)'s group reveal that TDP-43 forms amyloid filaments with a new fold in the most common type of frontotemporal lobar degeneration: [https://t.co/MAJSlt9SMo](https://t.co/MAJSlt9SMo)[#LMBResearch](https://twitter.com/hashtag/LMBResearch?src=hash&ref_src=twsrc%5Etfw) [pic.twitter.com/77AhH84vlL](https://t.co/77AhH84vlL)
> 
> — MRC Laboratory of Molecular Biology (@MRC\_LMB) [August 2, 2023](https://twitter.com/MRC_LMB/status/1686774491609739264?ref_src=twsrc%5Etfw)

> new release2
> 
> 8JR9: PCO371 bound to human PTH1R
> 
> "A Cryo\_EM structure of class B G protein coupled receptors for 2 orally active small molecule agonists"  
> →"Conserved class B GPCR activation by a biased intracellular agonist"
> 
> Eric Xu lab. Nature. [pic.twitter.com/oj5DegCbF3](https://t.co/oj5DegCbF3)
> 
> — Hideaki E. Kato (@emeKato) [August 2, 2023](https://twitter.com/emeKato/status/1686634938895073280?ref_src=twsrc%5Etfw)

> new release1
> 
> 8F0J: CTR w/ Gs and Pramlintide analogue peptide San45
> 
> AMY3 Receptor w/ Gs and  
> 8F0K: San385  
> 8F2A: San385 (Cluster 5 conf)  
> 8F2B: San45
> 
> "Structure-based insight into development of selective and non-selective amylin and calcitonin receptor agonists"
> 
> Wootten lab. [pic.twitter.com/1TBUF4e6Z9](https://t.co/1TBUF4e6Z9)
> 
> — Hideaki E. Kato (@emeKato) [August 2, 2023](https://twitter.com/emeKato/status/1686633563821924352?ref_src=twsrc%5Etfw)

> Disease-specific tau filaments assemble via polymorphic intermediates. This is what had me so excited for the past few weeks! The amazing Sofia Lövestam has solved another 163 [#cryoEM](https://twitter.com/hashtag/cryoEM?src=hash&ref_src=twsrc%5Etfw) structures! 🥳🥳🥳A [#tweetorial](https://twitter.com/hashtag/tweetorial?src=hash&ref_src=twsrc%5Etfw) below. As always, with [@MichelGoed](https://twitter.com/MichelGoed?ref_src=twsrc%5Etfw).[https://t.co/bQTM8gN9sO](https://t.co/bQTM8gN9sO)
> 
> — Sjors Scheres (@SjorsScheres) [July 27, 2023](https://twitter.com/SjorsScheres/status/1684467276244828160?ref_src=twsrc%5Etfw)

> Excited to share the structure of an orphan [#GPCR](https://twitter.com/hashtag/GPCR?src=hash&ref_src=twsrc%5Etfw) GPR179 bound to an extracellular cell adhesion molecule Pikachurin (EGFLAM) which is key to light reception. Great collaboration with [@fornerislab](https://twitter.com/fornerislab?ref_src=twsrc%5Etfw), [@AppuKSingh\_IITK](https://twitter.com/AppuKSingh_IITK?ref_src=twsrc%5Etfw) and Pat Griffin. [https://t.co/CGm0AvdD9r](https://t.co/CGm0AvdD9r) [pic.twitter.com/UDo09iEzr1](https://t.co/UDo09iEzr1)
> 
> — Kirill Martemyanov Lab (@KLabGPCR) [July 25, 2023](https://twitter.com/KLabGPCR/status/1683914628999573504?ref_src=twsrc%5Etfw)

## The weird and wonderful

> Happy to share our work on the structure of the human outer kinetochore KMN network complex
> 
> Many thanks to David Barford, Dom Bellini, [@JYang188](https://twitter.com/JYang188?ref_src=twsrc%5Etfw) and [@ZhangZiguo](https://twitter.com/ZhangZiguo?ref_src=twsrc%5Etfw) for working with me on this project.[https://t.co/BQuK5cmwKc](https://t.co/BQuK5cmwKc) [pic.twitter.com/v8E78o53LX](https://t.co/v8E78o53LX)
> 
> — Stanislau Yatskevich (@StanislauY) [August 8, 2023](https://twitter.com/StanislauY/status/1688791592688074752?ref_src=twsrc%5Etfw)

## Sample preparation

> Shameless plug. Here's a new protocol paper for EMPEM. 😊[https://t.co/lss3jeTTNK](https://t.co/lss3jeTTNK)
> 
> — EMproblems (@CryoEMprobs) [August 1, 2023](https://twitter.com/CryoEMprobs/status/1686439337272168450?ref_src=twsrc%5Etfw)

> [https://t.co/9FLfRdZfw0](https://t.co/9FLfRdZfw0)  
> Next generation of membrane protein single particle cryo-EM is here. Amazing works from my colleagues [@Chen\_Zhao\_CZhao](https://twitter.com/Chen_Zhao_CZhao?ref_src=twsrc%5Etfw) and [@XiaoTao214426](https://twitter.com/XiaoTao214426?ref_src=twsrc%5Etfw). High resolution structure of Slo1 in near native conditions - no detergent at all!
> 
> — George Vaisey (@GVaisey) [April 25, 2023](https://twitter.com/GVaisey/status/1650921834546700288?ref_src=twsrc%5Etfw)

> Our NEW Ethane Cryostat for the MiTeGen Manual Plunge Cooler [https://t.co/CFRKMvKKbX](https://t.co/CFRKMvKKbX) or Vitrobot: temp-controlled liquid ethane for user-friendly vitrification, reducing risks to your samples and equipment - Learn More [https://t.co/4gtksZ6beX](https://t.co/4gtksZ6beX) [#cryoem](https://twitter.com/hashtag/cryoem?src=hash&ref_src=twsrc%5Etfw) [pic.twitter.com/ipGYVMvsPo](https://t.co/ipGYVMvsPo)
> 
> — MiTeGen (@MiTeGen) [July 25, 2023](https://twitter.com/MiTeGen/status/1683673429931880448?ref_src=twsrc%5Etfw)

> When the [@thermosciEMSpec](https://twitter.com/thermosciEMSpec?ref_src=twsrc%5Etfw) [#Glacios](https://twitter.com/hashtag/Glacios?src=hash&ref_src=twsrc%5Etfw) Autoloader vacuum sucks (or rather doesn't as it should), you inspect its valve to the outside world - and find this… Simple explanations are a wonderful thing. [#cryoEM](https://twitter.com/hashtag/cryoEM?src=hash&ref_src=twsrc%5Etfw) [@MPIbp](https://twitter.com/MPIbp?ref_src=twsrc%5Etfw) [pic.twitter.com/3fiO7rUTda](https://t.co/3fiO7rUTda)
> 
> — Sonja Welsch (@sonjawelsch) [July 24, 2023](https://twitter.com/sonjawelsch/status/1683566852629200896?ref_src=twsrc%5Etfw)

## Better imaging

> Radiolysis of Thin Water Ice in Electron Microscopy | The Journal of Physical Chemistry C [https://t.co/CP7COjjULp](https://t.co/CP7COjjULp)
> 
> — Wim Hagen (@WimJHH) [August 2, 2023](https://twitter.com/WimJHH/status/1686787971729551360?ref_src=twsrc%5Etfw)

> Square electrons! Get your square electron beams!  
> Replace your C2 with a square aperture. Benefits include optimal tiling in cryoEM & cryoET and no resolution loss.  
> Paper: [https://t.co/WsI3p8561l](https://t.co/WsI3p8561l)  
> Study by [@eydchua](https://twitter.com/eydchua?ref_src=twsrc%5Etfw), Michael Alink, [@MishaKopylov3](https://twitter.com/MishaKopylov3?ref_src=twsrc%5Etfw), & [@demarco\_lab](https://twitter.com/demarco_lab?ref_src=twsrc%5Etfw), [@SEMC\_NYSBC](https://twitter.com/SEMC_NYSBC?ref_src=twsrc%5Etfw) [https://t.co/RErlw8hdlF](https://t.co/RErlw8hdlF) [pic.twitter.com/TWAOV4sROn](https://t.co/TWAOV4sROn)
> 
> — Alex J Noble (@alexjamesnoble) [July 31, 2023](https://twitter.com/alexjamesnoble/status/1685992659855306753?ref_src=twsrc%5Etfw)

## Processing and IT

> 🔔Don't miss this opportunity and Join our [#singleparticlecryoEM](https://twitter.com/hashtag/singleparticlecryoEM?src=hash&ref_src=twsrc%5Etfw) data processing workshop at [#bio21](https://twitter.com/hashtag/bio21?src=hash&ref_src=twsrc%5Etfw) [#IHIC](https://twitter.com/hashtag/IHIC?src=hash&ref_src=twsrc%5Etfw) on 23rd-25th of October. Register here:[https://t.co/wG0VWWRUqg](https://t.co/wG0VWWRUqg). Registration closes on September 15th.
> 
> — Sepideh Valimehr (@SValimehr) [August 4, 2023](https://twitter.com/SValimehr/status/1687421674185261057?ref_src=twsrc%5Etfw)

> Any [#cryoEM](https://twitter.com/hashtag/cryoEM?src=hash&ref_src=twsrc%5Etfw) facility users/staff with a take on ideal balance of EM user guidance vs. freedom?🧐Users working through scope hiccups learn a lot, but create chaos. Those shielded from hiccups generate more data, but not fewer issues (just different). And never grow into experts.🤷🏻‍♀️ [pic.twitter.com/34pkVPr3cc](https://t.co/34pkVPr3cc)
> 
> — Sonja Welsch (@sonjawelsch) [July 28, 2023](https://twitter.com/sonjawelsch/status/1684912872936095744?ref_src=twsrc%5Etfw)

## Thoughts and opinions

> Henderson and Hasnain: \`Cryo-EM': electron cryomicroscopy, cryo electron microscopy or something else? [#Nomenclature](https://twitter.com/hashtag/Nomenclature?src=hash&ref_src=twsrc%5Etfw) [#CryoEM](https://twitter.com/hashtag/CryoEM?src=hash&ref_src=twsrc%5Etfw) [#Standardization](https://twitter.com/hashtag/Standardization?src=hash&ref_src=twsrc%5Etfw) [@livuni](https://twitter.com/LivUni?ref_src=twsrc%5Etfw)... [#IUCr](https://twitter.com/hashtag/IUCr?src=hash&ref_src=twsrc%5Etfw) [https://t.co/JCvvh0s5Lf](https://t.co/JCvvh0s5Lf)
> 
> — IUCrJ (@IUCrJ) [August 11, 2023](https://twitter.com/IUCrJ/status/1689788787256078337?ref_src=twsrc%5Etfw)

> When you read posts like this, it's clear that the biopharma industry has done a terrible job communicating the value prop of our industry.
> 
> A reminder on some of those points:
> 
> Grab a coffee, this will be a long one
> 
> ✔️ Drug spending is far less than hospital care & physician… [https://t.co/CZfYhBVTcp](https://t.co/CZfYhBVTcp) [pic.twitter.com/nn4MzWQVbL](https://t.co/nn4MzWQVbL)
> 
> — Andrew Pannu (@andrewpannu) [August 13, 2023](https://twitter.com/andrewpannu/status/1690718646178578432?ref_src=twsrc%5Etfw)

> Can cryoEM go back to the more entertaining topics? 2/3 Nyquist, FSC, near-atomic, p-length in 1/Å?
> 
> — Wim Hagen (@WimJHH) [August 12, 2023](https://twitter.com/WimJHH/status/1690429731374587904?ref_src=twsrc%5Etfw)

> This!  
> Proteins are there as part of a huge, stochastic system. Not to fulfil a purpose.
> 
> A cell is not a car. You can't look at one doohicky and say "that's there in order to pump fuel". Because nobody designed it, and proteins aren't engineered for a unique function. [#evolution](https://twitter.com/hashtag/evolution?src=hash&ref_src=twsrc%5Etfw) [https://t.co/OBogR4CNzt](https://t.co/OBogR4CNzt)
> 
> — Robert Insall @robinsall@mas.to (@robinsall) [August 9, 2023](https://twitter.com/robinsall/status/1689303843840897024?ref_src=twsrc%5Etfw)

> When I started out in science, I ran gels. It takes a day or two to master and then you just do it hundreds of times. If you fail, it costs your time only & you try again.  
> CryoEM takes months to master and a typical PhD student will solve <5 structures. How do we train?
> 
> — Jason Kaelber (@Kaelberviridae) [July 31, 2023](https://twitter.com/Kaelberviridae/status/1686118991050465283?ref_src=twsrc%5Etfw)

## Biotech news and drug discovery technologies

> This week on the Readout LOUD:
> 
> Wegovy! Of course.
> 
> Can [$LLY](https://twitter.com/search?q=%24LLY&src=ctag&ref_src=twsrc%5Etfw) become the first trillion-dollar drug maker?
> 
> We discuss w/ Jared Holz, biotech market strategist at Mizuho. [https://t.co/B2yIMPpOU8](https://t.co/B2yIMPpOU8)
> 
> — Adam Feuerstein (@adamfeuerstein) [August 10, 2023](https://twitter.com/adamfeuerstein/status/1689735850999836672?ref_src=twsrc%5Etfw)

> Meanwhile, over at Indianapolis [@EliLillyandCo](https://twitter.com/EliLillyandCo?ref_src=twsrc%5Etfw) Tirzepatide is driving tremendous sales growth [#T2D](https://twitter.com/hashtag/T2D?src=hash&ref_src=twsrc%5Etfw) and innovative oral GLP-1 Orforglipron and triple G Retatrutide are now in P3 and poised to move the needle in promising new options for [#T2D](https://twitter.com/hashtag/T2D?src=hash&ref_src=twsrc%5Etfw) [#obesity](https://twitter.com/hashtag/obesity?src=hash&ref_src=twsrc%5Etfw) [#CVD](https://twitter.com/hashtag/CVD?src=hash&ref_src=twsrc%5Etfw) [https://t.co/PQofrSnkVa](https://t.co/PQofrSnkVa) [pic.twitter.com/sSw5DEC1dx](https://t.co/sSw5DEC1dx)
> 
> — Daniel J Drucker (@DanielJDrucker) [August 8, 2023](https://twitter.com/DanielJDrucker/status/1688921527306407936?ref_src=twsrc%5Etfw)

> Wow, wow, wow!
> 
> In SELECT trial of patients with obesity (mean BMI 33, n>17,000) & prior atherosclerotic cardiovascular disease (but no diabetes),
> 
> GLP-1 agonist semaglutide 2.4mg once-weekly
> 
> reduced risk of CV death, heart attack, or stroke (RRR 20%)[https://t.co/BQvWUujknh](https://t.co/BQvWUujknh) [pic.twitter.com/aotdqUKs2K](https://t.co/aotdqUKs2K)
> 
> — Sek Kathiresan MD (@skathire) [August 8, 2023](https://twitter.com/skathire/status/1688856249918484481?ref_src=twsrc%5Etfw)

> The [@US\_FDA](https://twitter.com/US_FDA?ref_src=twsrc%5Etfw) just approved the first oral medication indicated to treat postpartum depression in adults. [https://t.co/jDNFI2HktH](https://t.co/jDNFI2HktH) [https://t.co/YQ9PIiez8x](https://t.co/YQ9PIiez8x)
> 
> — National Institute of Mental Health (NIMH) (@NIMHgov) [August 7, 2023](https://twitter.com/NIMHgov/status/1688610590854713344?ref_src=twsrc%5Etfw)

> On GLP-1s & the new weight loss drugs, Pfizer CEO said: "this is only the beginning of this space. Clearly the unmet medical need is huge--obesity. Lilly & Novo Nordisk are here very successfully with two products that are injectable. There is a lot of market research conducted… [https://t.co/fBzUvt0RS5](https://t.co/fBzUvt0RS5)
> 
> — Pearl Freier (@PearlF) [August 1, 2023](https://twitter.com/PearlF/status/1686494083936555008?ref_src=twsrc%5Etfw)

> Apparently this phenomenon has a name: Pipeline herding. What a waste of time and money, especially in oncology [https://t.co/5Z9USkPp1V](https://t.co/5Z9USkPp1V) [https://t.co/ivHjbMl1w1](https://t.co/ivHjbMl1w1) [pic.twitter.com/EH1B8ePfHt](https://t.co/EH1B8ePfHt)
> 
> — Ohad Hammer (@ohadhammer) [July 31, 2023](https://twitter.com/ohadhammer/status/1686156438312284160?ref_src=twsrc%5Etfw)

> Some discouraging stats from a new analysis of big pharma R&D productivity: "On average, a big pharma company spent $4.4 billion annually in R&D and launched 0.78 new drugs. The peer group's R&D efficiency (2001–2020) is $6.16 billion (total R&D spending per new drug)" [pic.twitter.com/QL0xEArTtP](https://t.co/QL0xEArTtP)
> 
> — Alex Telford (@Atelfo) [July 31, 2023](https://twitter.com/Atelfo/status/1686130948591538176?ref_src=twsrc%5Etfw)

> Mirror mirror on the IP wall- which GLP-1- based medicines have the strongest patent protection of them all? [https://t.co/Ur2v3KrKbz](https://t.co/Ur2v3KrKbz)
> 
> — Daniel J Drucker (@DanielJDrucker) [July 28, 2023](https://twitter.com/DanielJDrucker/status/1685012879177629697?ref_src=twsrc%5Etfw)

## About MiTeGen

MiTeGen, founded in 2004 by Cornell University Professor Robert Thorne, is a leading provider of innovative technologies for cryo-EM, crystallography, and other techniques used for probing small molecule and biomolecular structure and function. Our mission is to support researchers in achieving the best possible results throughout the entire process, from sample preparation to data collection.

With a strong emphasis on collaboration, we actively work with academic, government, and industrial researchers in over 40 countries to develop and deliver new tools and methods. Our products have gained recognition and trust within the scientific community, as they have been cited in over 4,500 published research articles. By leveraging concepts and technologies from physics and related fields, we tackle practical challenges faced by our friends and collaborators in the life sciences and other disciplines.

Driven by a passion for cryo cooling, we would like to showcase three of our innovative cryo-EM solutions:

[Manual Plunge Cooler and Precision Ethane Cryostat:](https://www.mitegen.com/product/manual-plunger-cooler-and-precision-cryostat/)

Our Manual Plunge Cooler and Precision Cryostat are specifically designed to streamline and optimize your cryo-EM sample vitrification workflow. These systems consist of three components that can be obtained individually or as a complete package, ensuring efficient and successful sample preparation.

[Cryo-EM Starter Kits:](https://www.mitegen.com/product-category/cryo-em/cryo-em-starter-kits/)

Our Cryo-EM starter kits are curated to equip your laboratory with all the necessary tools conveniently packaged together. These kits are ideal for labs aiming to perform basic grid and sample preparation for cryo-EM within their own facility, even on a reduced budget. The kit includes components essential for cryo-EM sample preparation, as well as sample storage and transport solutions.

[Cryo-EM AutoGrid Cassette Puck:](https://www.mitegen.com/product/cryoem-autogrid-cassette-puck/)

Our latest addition, the Cryo-EM AutoGrid Cassette Storage and Shipping puck, builds upon the success of our 2nd generation Cryo-EM Puck. This innovative solution allows users to screen samples on a instrument and seamlessly ship the same AutoGrid cassette puck to a collection facility. It also serves as a convenient storage option for facilities, enabling them to store their cassettes in the puck canes designed to fit into cassette loading stations.

These cryo-EM solutions exemplify our dedication to enhancing cryo cooling capabilities and simplifying workflows in the field of cryo-EM. MiTeGen continues to push the boundaries of innovation, enabling researchers to advance their structural biology studies with greater ease and efficiency.

[Contact us at MiTeGen](https://www.mitegen.com/booth/) today to arrange a no obligation consultation to learn how we can help you with your research.

[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## Related posts

[![](https://cryoduck.com/hs-fs/hubfs/Hottest%20tweets-3.png?height=200&name=Hottest%20tweets-3.png)](https://cryoduck.com/blog/tweets-0923)

[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## [MiTeGen Hottest Tweets in SBDD (09/23)](https://cryoduck.com/blog/tweets-0923)

![Picture of Mazdak Radjainia](https://cryoduck.com/hs-fs/hubfs/PhotoSessions.nl-PWW_9643-bewerkt.jpg?width=50&name=PhotoSessions.nl-PWW_9643-bewerkt.jpg) [Mazdak Radjainia](https://cryoduck.com/blog/author/mazdak-radjainia) 

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[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## [MiTeGen Hottest Tweets in SBDD (07/23)](https://cryoduck.com/blog/tweets-0723)

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Here are your MiTeGen Hottest Tweets in SBDD, showcasing incredibly beautiful structures of...

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[MiTeGen](https://cryoduck.com/blog/tag/mitegen), [hottest tweets](https://cryoduck.com/blog/tag/hottest-tweets)

## [MiTeGen Hottest Tweets in SBDD (04/24)](https://cryoduck.com/blog/tweets-0424)

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 Apr 19, 2024 10:00:57 PM

Here are your MiTeGen Hottest Tweets in SBDD, featuring heated discussions about the Inflation...

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